Information Requested for MedWatch
Reports of Valvular Dysfunction
with use of Appetite Suppressant Drugs
1. Patient age, sex, weight, height, blood pressure.
2. Daily dosage of fenfluramine, dexfenfluramine,
phentermine.
3. Duration of use of appetite suppressant drugs.
4. If patient was no longer taking appetite suppressant
drugs at the time of echocardiography, the interval of time since stopping use of these
products.
5. Clinical history including symptoms (if any) and
presence/absence of an audible cardiac murmur.
6. Echocardiogram results:
- Presence of regurgitation at each valve, especially at the
aortic and mitral valves.
- Severity grading of regurgitation.
- Presence of pulmonary hypertension and estimated pulmonary
artery pressure.
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